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Post-doctoral researcher

Wetenschappelijke functies
Omvang (fte)
1.0
Extern/intern
Extern
Locatie
Leiden
Geplaatst op
30 maart 2021
Sluitingsdatum
31 mei 2021
The Faculty of Science / the Institute for Biology is looking for a
Post-doctoral researcher: development of new (semi)synthetic lipopeptide antibiotics
Key responsibilities
Synthesis and semisynthesis of new lipopeptide antibiotics;
Evaluation of
in vitro
antibiotic activity and cell-based toxicity;
Organization of
in vivo
stuies (with an industrial partner).
Selection criteria

Experience in:
Organic synthesis with specific expertise in peptide chemistry;
The use HPLC and MS techniques for purifying and characterizing biomolecules;
Antibacterial assays (i.e.
in vitro
MIC evaluation);
Biochemical assays (i.e. enzyme inhibition, isothermal titration calorimetry);
Graphpad prism, Chemdraw, PyMol, Chimera, and other relevant software packages.
Our organisation
The Faculty of Science is a world-class faculty where staff and students work together in a dynamic international environment. It is a faculty where personal and academic development are top priorities. Our people are committed to expand fundamental knowledge by curiosity and to look beyond the borders of their own discipline; their aim is to benefit science, and to make a contribution to addressing the major societal challenges of the future.

The research carried out at the Faculty of Science is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The research activities are organised in eight institutes. These institutes offer eight bachelor’s and twelve master’s programmes. The faculty has grown strongly in recent years and now has more than 2300 staff and almost 5000 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where university and business life come together.

For more information, see the website of the
.
The Biological Chemistry Group is part of the Institute of Biology Leiden
(IBL).
The group applies bioorganic chemistry and chemical biology approaches to address fundamental questions and societal challenges in the fields of infectious disease and epigenetics. The IBL is an integral part of a thriving scientific environment within our Faculty of Sciences that also includes the Naturalis Biodiversity Centre, the Leiden University Medical Centre, and the Leiden Bioscience Park. The IBL offers an exciting, internationally oriented, and inclusive place to work and study.

Terms and conditions
We offer a full-time, two year term position, start date negotiable but ideally starting in mid-to-late 2021. Salary range
from € 3.061,- to € 3.353,- gross per month (pay scale 10) in accordance with the Collective Labour Agreement for Dutch Universities).
Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses(8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break.

For
, see the website.
Diversity
Leiden
University
is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.
Information
Enquiries can be made Prof. Nathaniel Martin, email
. If you have any questions about the procedure, please contact Sylvia Maas, email
.
Applications
To apply for this vacancy, please send an email to
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